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March 18, 2008

Diabetes not two diseases but three at least

Traditional Type 1 and Type 2 diabetes are both multi-genic on the “nature” side of their cause. Well, now, scientists are finding several varieties of single-gene diabetes. And, we’re learning more about the traditional two types as well:
That brings us to the 16 genes discovered so far to play a role in Type 2 diabetes, and at least 14 in Type 1.

Surprisingly, the Type 2 genes don't affect how the body uses insulin, thought to be the trigger. Instead, they alter how the pancreas makes insulin in the first place, explains Dr. David Altshuler of Harvard and the Massachusetts Institute of Technology.

What this means? More targeted medications, and possibly more targeted dietetic suggestions, too.

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